The study included follow-up data in 14 patients.How does BTX-A affect the process of scar formation? "Temporary muscular paralysis induced by BTX-A could decrease movement and stress around a healing wound," Dr. By several measures, the final appearance of the scar was significantly better on the half treated with BTX-A.The study is published in the Plastic and Reconstructive Surgery.The authors noted some important limitations of their preliminary study, particularly the small number of patients included. The patients averaged 12 years of age.Six months later, independent plastic surgeons made measurements and rated the appearance of both sides of the scar.
The Botox-treated sides were also lower and narrower than then comparison sides.76 on the half treated with BTX-A versus 4. Lin and coauthors speculated.Injection of BTX-A - best known by the brand name Botox - is widely used for the treatment of facial lines and wrinkles.In each patient, half of the facial scar was randomly assigned to treatment with BTX-A or inactive saline (placebo) solution, injected immediately at the end of surgery. Most were undergoing surgery for some type of disfiguring facial birthmarks, such as a melanocytic nevus or port wine stain.They cited previous studies suggesting that BTX-A might also inhibit certain cells (fibroblasts) and mediators involved in scar.